AUTISM SPECTRUM DISORDERS
In addition to basic research, the Araya lab at the Ste Justine Children's Hospital Research Centre is actively studying a model of Fragile X syndrome, a genetic condition that causes a range of developmental delays, learning disabilities and cognitive impairments and is the most common known cause of Autism.
In 2021 the Araya lab added a Shank3 mutation model of autism spectrum disorders
to its research projects.
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Mitchell DE, Miranda-Rottmann S, Blanchard MG, Araya R.
Altered integration of excitatory inputs onto the basal dendrites of layer 5 pyramidal neurons in a mouse model of Fragile X Syndrome. https://www.pnas.org/doi/abs/10.1073/pnas.2208963120