Fragile X Syndrome and Shank3 mutation

In addition to basic research, the Araya lab at the Ste Justine Children's Hospital Research Centre is actively studying a model of Fragile X syndrome, a genetic condition that causes a range of developmental delays, learning disabilities and cognitive impairments and is the most common known cause of Autism.

In 2021 the Araya lab added a Shank3 mutation model of autism spectrum disorders

to its research projects.

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Funding was initially provided by SRCF and a CIHR grant.

2022
Publication Announcement

Mitchell DE, Miranda-Rottmann S, Blanchard MG, Araya R.

Altered integration of excitatory inputs onto the basal dendrites of layer 5 pyramidal neurons in a mouse model of Fragile X Syndrome. bioRxiv. 2022.03.14.484306;

doi:https://doi.org/10.1101/2022.03.14.484306

Dr Diana Mitchell

"QART seeks to build a collaborative learning community with fellows at the center. Successful trainees will contribute to building an inclusive learning environment that promotes dialogue, critical thinking, and exchange with cross-sector stakeholders including other researchers, professionals, decision-makers, and the autism community"